The thematic areas explored include disability rights, LGBTQI+ rights, Indigenous and Afro-descendant communities’ rights, educational attainment, sexual and reproductive health and rights, gender-based violence, child marriage, and women’s political and economic participation. In the context of democratic backsliding, authoritarian rule, political repression, and increasing international isolation under Nicaragua’s Sandinista National Liberation Front/ Daniel Ortega’s presidency, posts need to centre the commitment to ‘do no harm’ and avoid backlash to minority and vulnerable groups and support (to the extent possible) civil society efforts to navigate the closure of civic spaces, while building momentum for accountability for human rights violations.